Windows workflow 4.5 - Send notifications at regular intervals

Windows workflow 4.5 - Send notifications at regular intervals

I am having an approval workflow. The client is asp.net mvc 4 and the
client calls out to a WEB API. This WEB API in turn hosts the WF using
WorkflowAplication class. The scenario here is, if a request is not
approved for a certain time, i need the persisted workflow to load send an
email and persist again. Is this scenario possible somehow using WF 4.5